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After Gastric Bypass, 65% Showed Improved Hypertension

HUNTINGTON BEACH, CALIF. — In a study of 95 morbidly obese patients with hypertension, 46% had complete resolution of their hypertension and another 19% showed some improvement 12 months after laparoscopic Roux-en-Y gastric bypass surgery, Dr. Marcelo W. Hinojosa reported at the Academic Surgical Congress.

It's well known that when obese patients lose weight, their hypertension often improves, and when obese patients have gastric bypass surgery, they usually lose weight. It's therefore reasonable to assume that when obese patients have gastric bypass surgery, their hypertension will probably improve. The study data provided evidence to support these relationships.

The research was a retrospective review. All of the patients in the study were taking at least one antihypertensive medication, and 40% were on two or more. Their mean age was 47 years at the time of surgery, and their mean body mass index was 47 kg/m

As expected, the surgery resulted in significant weight loss. Within 1 month after the surgery, patients had lost an average of 23% of their excess weight, and that increased to 66% at the end of 12 months.

Dr. Hinojosa and his colleagues at the University of California, Irvine, defined complete resolution of hypertension as a systolic blood pressure less than 140 mm Hg and diastolic pressure less than 80 mm Hg without the use of any antihypertensive medication. They defined improvement as maintaining that pressure or less while decreasing the requirement for antihypertensives.

Within 1 month, the average blood pressure declined from 139.8/79.9 to 123.3/75.3, a significant difference. At 12 months, the group showed evidence of further decline, with an average blood pressure of 120.0/71.3.

At 1 month, 25% of the patients had complete resolution of their hypertension, and 36% showed some improvement. The proportion showing complete resolution increased to 41% at 6 months and 46% at 12 months. The proportion showing some improvement was 21% at 6 months and 19% at 12 months.

The patients in the study had experienced hypertension for an average of approximately 6 years. The investigators determined that the patients with a disease duration of less than 4 years were significantly more likely to have complete resolution of their hypertension than were those with a longer duration of disease.

Dr. Hinojosa declared that he had no relevant financial relationships associated with this study.

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HUNTINGTON BEACH, CALIF. — In a study of 95 morbidly obese patients with hypertension, 46% had complete resolution of their hypertension and another 19% showed some improvement 12 months after laparoscopic Roux-en-Y gastric bypass surgery, Dr. Marcelo W. Hinojosa reported at the Academic Surgical Congress.

It's well known that when obese patients lose weight, their hypertension often improves, and when obese patients have gastric bypass surgery, they usually lose weight. It's therefore reasonable to assume that when obese patients have gastric bypass surgery, their hypertension will probably improve. The study data provided evidence to support these relationships.

The research was a retrospective review. All of the patients in the study were taking at least one antihypertensive medication, and 40% were on two or more. Their mean age was 47 years at the time of surgery, and their mean body mass index was 47 kg/m

As expected, the surgery resulted in significant weight loss. Within 1 month after the surgery, patients had lost an average of 23% of their excess weight, and that increased to 66% at the end of 12 months.

Dr. Hinojosa and his colleagues at the University of California, Irvine, defined complete resolution of hypertension as a systolic blood pressure less than 140 mm Hg and diastolic pressure less than 80 mm Hg without the use of any antihypertensive medication. They defined improvement as maintaining that pressure or less while decreasing the requirement for antihypertensives.

Within 1 month, the average blood pressure declined from 139.8/79.9 to 123.3/75.3, a significant difference. At 12 months, the group showed evidence of further decline, with an average blood pressure of 120.0/71.3.

At 1 month, 25% of the patients had complete resolution of their hypertension, and 36% showed some improvement. The proportion showing complete resolution increased to 41% at 6 months and 46% at 12 months. The proportion showing some improvement was 21% at 6 months and 19% at 12 months.

The patients in the study had experienced hypertension for an average of approximately 6 years. The investigators determined that the patients with a disease duration of less than 4 years were significantly more likely to have complete resolution of their hypertension than were those with a longer duration of disease.

Dr. Hinojosa declared that he had no relevant financial relationships associated with this study.

ELSEVIER GLOBAL MEDICAL NEWS

HUNTINGTON BEACH, CALIF. — In a study of 95 morbidly obese patients with hypertension, 46% had complete resolution of their hypertension and another 19% showed some improvement 12 months after laparoscopic Roux-en-Y gastric bypass surgery, Dr. Marcelo W. Hinojosa reported at the Academic Surgical Congress.

It's well known that when obese patients lose weight, their hypertension often improves, and when obese patients have gastric bypass surgery, they usually lose weight. It's therefore reasonable to assume that when obese patients have gastric bypass surgery, their hypertension will probably improve. The study data provided evidence to support these relationships.

The research was a retrospective review. All of the patients in the study were taking at least one antihypertensive medication, and 40% were on two or more. Their mean age was 47 years at the time of surgery, and their mean body mass index was 47 kg/m

As expected, the surgery resulted in significant weight loss. Within 1 month after the surgery, patients had lost an average of 23% of their excess weight, and that increased to 66% at the end of 12 months.

Dr. Hinojosa and his colleagues at the University of California, Irvine, defined complete resolution of hypertension as a systolic blood pressure less than 140 mm Hg and diastolic pressure less than 80 mm Hg without the use of any antihypertensive medication. They defined improvement as maintaining that pressure or less while decreasing the requirement for antihypertensives.

Within 1 month, the average blood pressure declined from 139.8/79.9 to 123.3/75.3, a significant difference. At 12 months, the group showed evidence of further decline, with an average blood pressure of 120.0/71.3.

At 1 month, 25% of the patients had complete resolution of their hypertension, and 36% showed some improvement. The proportion showing complete resolution increased to 41% at 6 months and 46% at 12 months. The proportion showing some improvement was 21% at 6 months and 19% at 12 months.

The patients in the study had experienced hypertension for an average of approximately 6 years. The investigators determined that the patients with a disease duration of less than 4 years were significantly more likely to have complete resolution of their hypertension than were those with a longer duration of disease.

Dr. Hinojosa declared that he had no relevant financial relationships associated with this study.

ELSEVIER GLOBAL MEDICAL NEWS

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